The Luma300™ is grounded in technology supported by a growing body of scientific studies and comprehensive reviews.
The following selection offers insight into the wide-ranging applications of photobiomodulation—from skin regeneration and pain reduction to muscle recovery and sleep support.
General:
Photobiomodulation-Underlying Mechanism and Clinical Applications
(pmc.ncbi.nlm.nih.gov/articles/PMC7356229)
Anti-Aging:
A Controlled Trial to Determine the Efficacy of Red and Near-Infrared Light Treatment in Patient Satisfaction, Reduction of Fine Lines, Wrinkles, Skin Roughness, and Intradermal Collagen Density Increase
(ncbi.nlm.nih.gov/pmc/articles/PMC3926176)
Low-level red plus near infrared lights combination induces expressions of collagen and elastin in human skin in vitro
(pubmed.ncbi.nlm.nih.gov/33594706)
Effects of infrared radiation on skin photo-aging and pigmentation
(pubmed.ncbi.nlm.nih.gov/16941737)
A prospective, randomized, placebo-controlled, double-blinded, and
split-face clinical study on LED phototherapy for skin rejuvenation
(sciencedirect.com/science/article/abs/pii/S1011134407000632)
Combined 633-nm and 830-nm led treatment of photoaging skin
(pubmed.ncbi.nlm.nih.gov/16989189)
Photodynamic photorejuvenation of the face with a combination of microneedling, red light, and broadband pulsed light
(onlinelibrary.wiley.com/doi/abs/10.1002/lsm.20905)
Skin Health:
Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring
(ncbi.nlm.nih.gov/pmc/articles/PMC4126803)
The effects of photobiomodulation therapy on inflammatory mediators, immune infiltration, and angiogenesis in a mouse model of rosacea
(pubmed.ncbi.nlm.nih.gov/36035005)
A dose-ranging, parallel group, split-face, single-blind phase II study of light emitting diode-red light (LED-RL) for skin scarring prevention
(link.springer.com/article/10.1186/s13063-019-3546-6)
Response of psoriasis to red laser light (630 nm) following systemic injection of hematoporphyrin derivative
(onlinelibrary.wiley.com/doi/abs/10.1002/lsm.1900040110)
Pain:
The Mechanisms and Efficacy of Photobiomodulation Therapy for Arthritis: A Comprehensive Review
(pmc.ncbi.nlm.nih.gov/articles/PMC10531845)
Current advances of photobiomodulation therapy in treating knee osteoarthritis
(frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2023.1286025/full)
Outcomes of whole-body photobiomodulation on pain, quality of life, leisure physical activity, kinesiophobia, self-efficacy, and pain catastrophizing in individuals with fibromyalgia: A triple-blinded randomized clinical trial
(frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2024.1264821/full)
Improvement of pain and disability in elderly patients with degenerative osteoarthritis of the knee treated with narrow-band light therapy
(pubmed.ncbi.nlm.nih.gov/1727843)
Mechanisms and applications of the anti-inflammatory effects of photobiomodulation
(aimspress.com/article/10.3934/biophy.2017.3.337)
Recovery:
Photobiomodulation in human muscle tissue: an advantage in sports performance?
(ncbi.nlm.nih.gov/pmc/articles/PMC5167494)
Low-level laser (light) therapy (LLLT) on muscle tissue: performance, fatigue and repair benefited by the power of light
(degruyterbrill.com/document/doi/10.1515/plm-2012-0032/html)
Effects of Light-Emitting Diode Therapy on Muscle Hypertrophy, Gene Expression, Performance, Damage, and Delayed-Onset Muscle Soreness: Case-control Study with a Pair of Identical Twins
(pubmed.ncbi.nlm.nih.gov/27088469)
Effect of phototherapy on delayed onset muscle soreness
(pubmed.ncbi.nlm.nih.gov/16875447)
830 nm light-emitting diode (led) phototherapy significantly reduced
return-to-play in injured university athletes: a pilot study
(pmc.ncbi.nlm.nih.gov/articles/PMC4846838)
Sleep & Energy:
Effects of Near-Infrared Light on Well-Being and Health in Human Subjects with Mild Sleep-Related Complaints: A Double-Blind, Randomized, Placebo-Controlled Study
(mdpi.com/2079-7737/12/1/60)
Photobiomodulation increases brain metabolic activity through a combination of red and near-infrared light
(pmc.ncbi.nlm.nih.gov/articles/PMC10786747)
Red Light and the Sleep Quality and Endurance Performance of Chinese Elite Female Basketball Players
(pmc.ncbi.nlm.nih.gov/articles/PMC3499892)
Transcranial Laser Photobiomodulation Improves Intracellular Signaling Pathways Linked to Cell Survival, Memory, and Glucose Metabolism in the Brain of Aged Rats
(frontiersin.org/journals/cellular-neuroscience/articles/10.3389/fncel.2021.683127/full)
810-nm Photobiomodulation Evokes Glutamate Release in Normal and Rotenone-Dysfunctional Cortical Nerve Terminals by Modulating Mitochondrial Energy Metabolism
(mdpi.com/2073-4409/14/2/67)
Weight Loss:
Low-Level Laser Therapy for Fat Layer Reduction: A Comprehensive Review
(pmc.ncbi.nlm.nih.gov/articles/PMC3769994)
The potential of phototherapy to reduce body fat, insulin resistance and "metabolic inflexibility" related to obesity in women undergoing weight loss treatment
(pubmed.ncbi.nlm.nih.gov/26220050)
Hair Growth:
Low-level laser (light) therapy (LLLT) for treatment of hair loss
(pubmed.ncbi.nlm.nih.gov/23970445/)
Comparison of the effects of 665 nm low level diode Laser Hat versus and a combination of 665 nm and 808nm low level diode Laser Scanner of hair growth in androgenic alopecia
(tandfonline.com/doi/abs/10.1080/14764172.2017.1326609)
Thyroid Health:
Low-level laser therapy in chronic autoimmune thyroiditis: a pilot study
(pubmed.ncbi.nlm.nih.gov/20662037)
Assessment of the Effects of Low-Level Laser Therapy on the Thyroid
Vascularization of Patients with Autoimmune Hypothyroidism
(pmc.ncbi.nlm.nih.gov/articles/PMC3534372/)